Biological data analysis often deals with lists of genes arising from various studies. The g:
Profiler toolset is widely used for finding biological categories enriched in gene lists …

Abstract The Principal Component Analysis (PCA) is a widely used method of reducing the
dimensionality of high-dimensional data, often followed by visualizing two of the …

Abstract g: Profiler (http://biit. cs. ut. ee/gprofiler/) is a public web server for characterising
and manipulating gene lists resulting from mining high-throughput genomic data. g: Profiler …

Functional enrichment analysis is a key step in interpreting gene lists discovered in diverse
high-throughput experiments. g: Profiler studies flat and ranked gene lists and finds …

Motivation: The continued progress in developing technological platforms, availability of
many published experimental datasets, as well as different statistical methods to analyze …

Functional interpretation of candidate gene lists is an essential task in modern biomedical
research. Here, we present the 2011 update of g: Profiler (http://biit. cs. ut. ee/gprofiler/), a …

Abstract g: Profiler (https://biit. cs. ut. ee/gprofiler) is a widely used gene list functional
profiling and namespace conversion toolset that has been contributing to reproducible …

Abstract g: Profiler is a reliable and up-to-date functional enrichment analysis tool that
supports various evidence types, identifier types and organisms. The toolset integrates many …

Background DNA epigenetic modifications, such as methylation, are important regulators of
tissue differentiation, contributing to processes of both development and cancer. Profiling the …

Aim: To develop a web tool for survival analysis based on CpG methylation patterns.
Materials & methods: We utilized methylome data from 'The Cancer Genome Atlas' and used …

Developmental neurotoxicity (DNT) and many forms of reproductive toxicity (RT) often
manifest themselves in functional deficits that are not necessarily based on cell death, but …

Seventy-five percent of breast cancers are estrogen receptor α positive (ER+). Research on
these tumors is hampered by lack of adequate in vivo models; cell line xenografts require …

The prognostic and diagnostic value of microRNA (miRNA) expression aberrations in lung
cancer has been studied intensely in recent years. However, due to the application of …

We present a web resource MEM (Multi-Experiment Matrix) for gene expression similarity
searches across many datasets. MEM features large collections of microarray datasets and …

Motivation: Increased availability of various genotyping techniques has initiated a race for
finding genetic markers that can be used in diagnostics and personalized medicine …

BACKGROUND: Enhanced apoptosis of keratinocytes is the main cause of eczema and
spongiosis in patients with the common inflammatory skin disease atopic dermatitis (AD) …

A prerequisite for successful embryo implantation is adequate preparation of receptive
endometrium and the establishment and maintenance of a viable embryo. The success of …

Dendritic cells (DCs) and macrophages (MFs) are important multifunctional immune cells.
Like other cell types, they express hundreds of different microRNAs (miRNAs) that are …

Transcription factor (TF) perturbation experiments give valuable insights into gene
regulation. Genome-scale evidence from microarray measurements may be used to identify …

Lung cancer is one of the deadliest types of cancer proven by the poor survival and high
relapse rates after surgery. Recently discovered microRNAs (miRNAs), small noncoding …